Cell membrane is a biological
membrane that separates the interior of all cells from
the outside environment (the extracellular space) The basic function of the cell membrane is to
protect the cell from its surroundings. The cell membrane controls the
movement of substances in and out of cells
composition
of cell membrane :
1-
Lipid
The cell membrane consists of three classes
of amphipathic lipids: phospholipids, glycolipids,
and sterols.
2-
carbohydrates :
Plasma membranes also contain carbohydrates,
predominantly glycoproteins, but with some glycolipids (cerebrosides and
gangliosides). Carbohydrates are important in the role of cell-cell recognition
in eukaryotes; they are located on the surface of the cell where they recognize
host cells and share information,
3-
protein
protein
are important for the cell , they are responsible for various biological
activities , membrane protein consist of 3 main type , integral protein , peripheral
protein and lipid anchored protein
1- transmembrane
proteins Span the membrane and
have a hydrophilic cytosolic domain, which interacts with internal molecules, a
hydrophobic membrane-spanning domain that anchors it within the cell membrane,
and a hydrophilic extracellular domain that interacts with external molecules.
2- peripheral protein associated
with peripheral regions of the lipid bilayer. These proteins tend to have only
temporary interactions with biological membranes, and once reacted, the
molecule dissociates to carry on its work in the cytoplasm. Some enzymes, some hormones
3- -lipid anchored Covalently
bound to single or multiple lipid molecules; hydrophobically insert into the
cell membrane and anchor the protein.
Function
of cell membrane
1-The
cell membrane surround the cytoplasm of living cell physically separating the
intracellular component from extracellular environment , it also play a role in
anchoring the cytoskeleton and in attachment to extracellular environment
2-Some
substances (small molecules, ions) such as carbon dioxide (CO2) and oxygen
(O2), can move across the plasma membrane by diffusion, which is a passive
transport process, osmosis involve
a solvent moving through semipermeable membrane from are of low concentration
to high
osmosis
3-Transmembrane
proteins extend through the lipid bilayer of the membranes; they function on
both sides of the membrane to transport molecules across it Nutrients, such as
sugars or amino acids, must enter the cell, and certain products of metabolism
must leave the cell.
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